Typhoid fever, also known as
enteric fever, is a bacterial
infection caused by the Salmonella
typhi bacteria. It is a severe and
life-threatening disease that
affects millions of people
worldwide, particularly in
developing countries with poor
sanitation and hygiene practices.
In this blog, we will cover
everything you need to know about
typhoid fever, including its
causes, symptoms, diagnosis,
treatment, and prevention.
Causes of Typhoid Fever:
Typhoid fever is caused by the
bacteria Salmonella typhi, which is
transmitted through contaminated
food and water. The bacteria enter
the body through the mouth, and
then travel to the small intestine,
where they multiply and infect the
bloodstream.
The bacteria are shed in the feces
and urine of infected individuals,
which can contaminate water sources
and food supplies. Poor sanitation
and hygiene practices, such as not
washing hands after using the
toilet, can contribute to the
spread of the disease.
Symptoms of Typhoid Fever:
The symptoms of typhoid fever can
vary in severity and duration, but
generally develop within 1-3 weeks
after exposure to the bacteria. The
most common symptoms include:
-
High Fever: The hallmark
symptom of typhoid fever is
a sustained high fever,
often reaching 103-104°F
(39-40°C).
-
Gastrointestinal symptoms:
Nausea, vomiting, and
diarrhea are common
symptoms of typhoid fever.
The diarrhea is often
bloody and can last for
several weeks.
-
Abdominal Pain: Patients
with typhoid fever may
experience abdominal pain,
particularly in the right
lower quadrant.
-
Headache: A headache is a
common symptom of typhoid
fever, and can be severe.
-
Rash: A rash may develop on
the trunk of the body in
some patients with typhoid
fever.
-
Weakness and fatigue:
Patients with typhoid fever
may experience weakness and
fatigue, which can persist
for several weeks after
recovery.
Diagnosis of Typhoid Fever:
Typhoid fever can be difficult to
diagnose because its symptoms can
mimic those of other illnesses,
such as malaria or viral hepatitis.
A blood test is typically used to
confirm the presence of the
Salmonella typhi bacteria.
In some cases, a stool sample may
be collected to identify the
bacteria, particularly in patients
with diarrhea. However, stool
samples may not always be reliable
because the bacteria may not be
present in the stool during the
early stages of the disease.
Treatment of Typhoid Fever:
Typhoid fever is a serious illness
that requires prompt treatment with
antibiotics. Antibiotics can help
to reduce the severity of the
symptoms and prevent complications.
Commonly used antibiotics for the
treatment of typhoid fever include
ciprofloxacin, azithromycin, and
ceftriaxone. The choice of
antibiotic depends on the severity
of the disease and the patient's
age and health status.
Patients with severe cases of
typhoid fever may require
hospitalization to receive
intravenous fluids and electrolytes
to prevent dehydration. In some
cases, surgery may be necessary to
remove a perforated intestine or
drain an abscess.
Prevention of Typhoid Fever:
The best way to prevent typhoid
fever is to practice good hygiene
and sanitation practices. This
includes washing hands thoroughly
with soap and water after using the
toilet, before preparing or eating
food, and after handling
contaminated materials.
Avoiding contaminated food and
water is also important in
preventing typhoid fever. Travelers
to developing countries with poor
sanitation and hygiene practices
should take precautions, such as
drinking bottled water and avoiding
raw or undercooked foods.
Vaccines are available for the
prevention of typhoid fever. The
two types of vaccines available are
the inactivated injectable vaccine
and the live attenuated oral
vaccine. The vaccine is recommended
for